Experience with the Use of Refrigerated

The history of the development of methods of bone transplantation is too long and the literature too voluminous to permit of any but the most superficial review in this paper. Ollier is credited with the first clinical experiment when in 1859 he transplanted a rabbit’s radius into an ununited fracture of the tibia. Macewen in 1881 first suggested the transplantation of bone from amputated limbs and Ponset in 1887 reported a clinical trial of this method. Bone transplantation was carried out sporadically by many surgeons but without much enthusiasm until Albee (1915) with his development of a sterile electrically driven motor saw popularised the method of using fresh autogenous bone grafts. During the following years this, with various technical modifications, became the standard surgical procedure. Carrel (1912) reported his extensive work on preservation and transplantation of various